6 Primary Causes of Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a type of high blood pressure that affects the pulmonary arteries and capillaries. Pulmonary arteries are the blood vessels that take blood from the right ventricles to the lungs. As the pressure in the pulmonary arteries and the smaller capillaries builds up, the heart must work harder to pump blood. It weakens the heart over time and can even lead to heart failure. The symptoms of PAH may not be noticeable initially, but as the condition worsens, they become pronounced. Some of them include difficulty breathing; fatigue; dizziness; swelling in the legs; arms, and abdomen; a bluish tinge on the lips; chest pain; a rapid pulse; and heart palpitations. There is no cure for PAH yet, but there is a range of treatments to lessen symptoms and lower the risk of complications. PAH develops when the pulmonary arteries and capillaries connecting the heart and lungs become constricted or damaged. A range of related conditions can trigger it, but the exact cause is unknown. Some of the possible causes of PAH are as follows: 1. Genetics Studies say that close to 20 percent of PAH cases are inherited. Genetic mutations in the BMPR2 gene are responsible for increasing one’s likelihood of developing PAH.